The hypoxia inducible factor HIF-1 functions as both a positive and negative modulator of aging

Por Leiser, Scott F., Kaeberlein, Matt
Publicado em 2010

Nrf2 Signaling, a Mechanism for Cellular Stress Resistance in Long-Lived Mice

Por Leiser, Scott F., Miller, Richard A.
Publicado em 2010

HIF-1 modulates longevity and healthspan in a temperature-dependent manner

Por Leiser, Scott F., Begun, Anisoara, Kaeberlein, Matt
Publicado em 2011

New insights into cell non-autonomous mechanisms of the C. elegans hypoxic response

Por Leiser, Scott F., Rossner, Ryan, Kaeberlein, Matt
Publicado no Worm (2016)

Flavin-containing monooxygenases in aging and disease: Emerging roles for ancient enzymes

Por Rossner, Ryan, Kaeberlein, Matt, Leiser, Scott F.
Publicado no J Biol Chem (2017)

Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1

Por Leiser, Scott F., Fletcher, Marissa, Begun, Anisoara, Kaeberlein, Matt
Publicado em 2013

Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone

Por Harper, James M., Salmon, Adam B., Leiser, Scott F., Galecki, Andrzej T., Miller, Richard A.
Publicado em 2006

Age-associated vulval integrity is an important marker of nematode healthspan

Por Leiser, Scott F., Jafari, Gholamali, Primitivo, Melissa, Sutphin, George L., Dong, Jingyi, Leonard, Alison, Fletcher, Marissa, Kaeberlein, Matt
Publicado no Age (Dordr) (2016)

Genetic interaction with temperature is an important determinant of nematode longevity

Por Miller, Hillary, Fletcher, Marissa, Primitivo, Melissa, Leonard, Alison, Sutphin, George L., Rintala, Nicholas, Kaeberlein, Matt, Leiser, Scott F.
Publicado no Aging Cell (2017)

Mechanisms of stress resistance in Snell dwarf mouse fibroblasts: enhanced antioxidant and DNA base excision repair capacity, but no differences in mitochondrial metabolism

Por Page, Melissa M., Salmon, Adam B., Leiser, Scott F., Robb, Ellen L., Brown, Melanie F., Miller, Richard A., Stuart, Jeffrey A.
Publicado em 2009

Cell Non-Autonomous Activation of Flavin-containing Monooxygenase Promotes Longevity and Healthspan

Por Leiser, Scott F., Miller, Hillary, Rossner, Ryan, Fletcher, Marissa, Leonard, Alison, Primitivo, Melissa, Rintala, Nicholas, Ramos, Fresnida J., Miller, Dana L., Kaeberlein, Matt
Publicado no Science (2015)