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HIF-1 modulates longevity and healthspan in a temperature-dependent manner

The hypoxia-inducible factor HIF-1 has recently been identified as an important modifier of longevity in the roundworm Caenorhabditis elegans. Studies have reported that HIF-1 can function as both a positive and negative regulator of lifespan, and several disparate models have been proposed for the...

詳細記述

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書誌詳細
主要な著者: Leiser, Scott F., Begun, Anisoara, Kaeberlein, Matt
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980873/
https://ncbi.nlm.nih.gov/pubmed/21241450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00672.x
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