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HIF-1 modulates longevity and healthspan in a temperature-dependent manner
The hypoxia-inducible factor HIF-1 has recently been identified as an important modifier of longevity in the roundworm Caenorhabditis elegans. Studies have reported that HIF-1 can function as both a positive and negative regulator of lifespan, and several disparate models have been proposed for the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980873/ https://ncbi.nlm.nih.gov/pubmed/21241450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00672.x |
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