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Genetic interaction with temperature is an important determinant of nematode longevity

As in other poikilotherms, longevity in C. elegans varies inversely with temperature; worms are longer‐lived at lower temperatures. While this observation may seem intuitive based on thermodynamics, the molecular and genetic basis for this phenomenon is not well understood. Several recent reports ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Miller, Hillary, Fletcher, Marissa, Primitivo, Melissa, Leonard, Alison, Sutphin, George L., Rintala, Nicholas, Kaeberlein, Matt, Leiser, Scott F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676069/
https://ncbi.nlm.nih.gov/pubmed/28940623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12658
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