טוען...
Cell Non-Autonomous Activation of Flavin-containing Monooxygenase Promotes Longevity and Healthspan
Stabilization of the hypoxia-inducible factor-1 (HIF-1) increases lifespan and healthspan in nematodes through an unknown mechanism. We report that neuronal stabilization of HIF-1 mediates these effects in C. elegans through a cell non-autonomous signal to the intestine resulting in activation of th...
שמור ב:
| הוצא לאור ב: | Science |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801033/ https://ncbi.nlm.nih.gov/pubmed/26586189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9257 |
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