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Flavin-containing monooxygenases in aging and disease: Emerging roles for ancient enzymes

Flavin-containing monooxygenases (FMOs) are primarily studied as xenobiotic metabolizing enzymes with a prominent role in drug metabolism. In contrast, endogenous functions and substrates of FMOs are less well understood. A growing body of recent evidence, however, implicates FMOs in aging, several...

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Pubblicato in:J Biol Chem
Autori principali: Rossner, Ryan, Kaeberlein, Matt, Leiser, Scott F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500783/
https://ncbi.nlm.nih.gov/pubmed/28515321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.779678
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