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The hypoxia inducible factor HIF-1 functions as both a positive and negative modulator of aging
In the past year and a half, five studies have independently established a direct connection between the hypoxic response transcription factor, HIF-1, and aging in Caenorhabditis elegans. These studies demonstrated that HIF-1 can both promote and limit longevity via pathways that are mechanistically...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018576/ https://ncbi.nlm.nih.gov/pubmed/20707608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2010.123 |
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