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Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone

Fibroblast cell lines were developed from skin biopsies of eight species of wild-trapped rodents, one species of bat, and a group of genetically heterogeneous laboratory mice. Each cell line was tested in vitro for their resistance to six varieties of lethal stress, as well as for resistance to the...

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Autors principals: Harper, James M., Salmon, Adam B., Leiser, Scott F., Galecki, Andrzej T., Miller, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766812/
https://ncbi.nlm.nih.gov/pubmed/17156084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00255.x
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