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Hormetic effect of rotenone in primary human fibroblasts

BACKGROUND: Rotenone inhibits the electron transfer from complex I to ubiquinone, in this way interfering with the electron transport chain in mitochondria. This chain of events induces increased levels of intracellular reactive oxygen species, which in turn can contribute to acceleration of telomer...

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Detalhes bibliográficos
Publicado no:Immun Ageing
Main Authors: Marthandan, Shiva, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Diekmann, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572608/
https://ncbi.nlm.nih.gov/pubmed/26380578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0038-8
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