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Hormetic effect of rotenone in primary human fibroblasts

BACKGROUND: Rotenone inhibits the electron transfer from complex I to ubiquinone, in this way interfering with the electron transport chain in mitochondria. This chain of events induces increased levels of intracellular reactive oxygen species, which in turn can contribute to acceleration of telomer...

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Détails bibliographiques
Publié dans:Immun Ageing
Auteurs principaux: Marthandan, Shiva, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Diekmann, Stephan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572608/
https://ncbi.nlm.nih.gov/pubmed/26380578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0038-8
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