Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence

BACKGROUND: Cellular senescence is induced either internally, for example by replication exhaustion and cell division, or externally, for example by irradiation. In both cases, cellular damages accumulate which, if not successfully repaired, can result in senescence induction. Recently, we determine...

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Опубликовано в: :Biol Res
Главные авторы: Marthandan, Shiva, Menzel, Uwe, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Kaether, Christoph, Diekmann, Stephan
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963952/
https://ncbi.nlm.nih.gov/pubmed/27464526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-016-0095-2
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