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Hormetic effect of rotenone in primary human fibroblasts

BACKGROUND: Rotenone inhibits the electron transfer from complex I to ubiquinone, in this way interfering with the electron transport chain in mitochondria. This chain of events induces increased levels of intracellular reactive oxygen species, which in turn can contribute to acceleration of telomer...

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Bibliografske podrobnosti
izdano v:Immun Ageing
Main Authors: Marthandan, Shiva, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Diekmann, Stephan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572608/
https://ncbi.nlm.nih.gov/pubmed/26380578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0038-8
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