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Nrf2 Signaling, a Mechanism for Cellular Stress Resistance in Long-Lived Mice

Transcriptional regulation of the antioxidant response element (ARE) by Nrf2 is important for the cellular adaptive response to toxic insults. New data show that primary skin-derived fibroblasts from the long-lived Snell dwarf mutant mouse, previously shown to be resistant to many toxic stresses, ha...

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Detalhes bibliográficos
Main Authors: Leiser, Scott F., Miller, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812245/
https://ncbi.nlm.nih.gov/pubmed/19933842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01145-09
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