miR-34a/SIRT6 in squamous differentiation and cancer

door Dotto, G Paolo, Lefort, Karine
Gepubliceerd in 2014

The Retinoid-Related Orphan Receptor RORα Promotes Keratinocyte Differentiation via FOXN1

door Dai, Jun, Brooks, Yang, Lefort, Karine, Getsios, Spiro, Dotto, G. Paolo
Gepubliceerd in 2013

Silencing of ASC in Cutaneous Squamous Cell Carcinoma

door Meier, Katharina, Drexler, Stefan K., Eberle, Franziska C., Lefort, Karine, Yazdi, Amir S.
Gepubliceerd in PLoS One (2016)

Negative control of CSL gene transcription by stress/DNA damage response and p53

door Menietti, Elena, Xu, Xiaoying, Ostano, Paola, Joseph, Jean-Marc, Lefort, Karine, Dotto, G. Paolo
Gepubliceerd in Cell Cycle (2016)

Impact of normalization on miRNA microarray expression profiling

door Pradervand, Sylvain, Weber, Johann, Thomas, Jérôme, Bueno, Manuel, Wirapati, Pratyaksha, Lefort, Karine, Dotto, G. Paolo, Harshman, Keith
Gepubliceerd in 2009

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer

door Lefort, Karine, Ostano, Gian Paola, Mello-Grand, Maurizia, Calpini, Valérie, Scatolini, Maria, Farsetti, Antonella, Dotto, Gian Paolo, Chiorino, Giovanna
Gepubliceerd in Oncotarget (2016)

Calcineurin and ATF3: opposite roles in squamous skin cancer

door Wu, Xunwei, Nguyen, Bach-Cuc, Dziunycz, Piotr, Chang, Sungeun, Brooks, Yang, Lefort, Karine, Hofbauer, Günther F.L., Dotto, G. Paolo
Gepubliceerd in 2010

The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response

door Mandinova, Anna, Lefort, Karine, di Vignano, Alice Tommasi, Stonely, Wesley, Ostano, Paola, Chiorino, Giovanna, Iwaki, Haruhi, Nakanishi, Jotaro, Dotto, G Paolo
Gepubliceerd in 2008

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

door Ayyanan, Ayyakannu, Civenni, Gianluca, Ciarloni, Laura, Morel, Catherine, Mueller, Nathalie, Lefort, Karine, Mandinova, Anna, Raffoul, Wassim, Fiche, Maryse, Dotto, Gian Paolo, Brisken, Cathrin
Gepubliceerd in 2006

EGFR signaling as a negative regulator of Notch1 gene expression : a differentiation/apoptosis control mechanism for proliferating keratinocytes and cancer cells

door Kolev, Vihren, Mandinova, Anna, Guinea-Viniegra, Juan, Hu, Bing, Lefort, Karine, Lambertini, Chiara, Neel, Victor, Dummer, Reinhard, Wagner, Erwin F., Dotto, G. Paolo
Gepubliceerd in 2008

CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma

door Dziunycz, Piotr J., Neu, Johannes, Lefort, Karine, Djerbi, Nadia, Freiberger, Sandra N., Iotzova-Weiss, Guergana, French, Lars E., Dotto, Gian-Paolo, Hofbauer, Günther F.
Gepubliceerd in PLoS One (2017)

HSD17B7 gene in self‐renewal and oncogenicity of keratinocytes from Black versus White populations

door Xu, Xiaoying, Tassone, Beatrice, Ostano, Paola, Katarkar, Atul, Proust, Tatiana, Joseph, Jean‐Marc, Riganti, Chiara, Chiorino, Giovanna, Kutalik, Zoltan, Lefort, Karine, Dotto, Gian Paolo
Gepubliceerd in EMBO Mol Med (2021)

Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis

door Hu, Bing, Lefort, Karine, Qiu, Wenying, Nguyen, Bach-Cuc, Rajaram, Renuga Devi, Castillo, Einar, He, Fenglei, Chen, Yiping, Angel, Peter, Brisken, Cathrin, Dotto, G. Paolo
Gepubliceerd in 2010

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer

door Brooks, Yang Sui, Ostano, Paola, Jo, Seung-Hee, Dai, Jun, Getsios, Spiro, Dziunycz, Piotr, Hofbauer, Günther F.L., Cerveny, Kara, Chiorino, Giovanna, Lefort, Karine, Dotto, G. Paolo
Gepubliceerd in 2014

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases

door Lefort, Karine, Mandinova, Anna, Ostano, Paola, Kolev, Vihren, Calpini, Valerie, Kolfschoten, Ingrid, Devgan, Vikram, Lieb, Jocelyn, Raffoul, Wassim, Hohl, Daniel, Neel, Victor, Garlick, Jonathan, Chiorino, Giovanna, Dotto, G. Paolo
Gepubliceerd in 2007

A miR-34a-SIRT6 axis in the squamous cell differentiation network

door Lefort, Karine, Brooks, Yang, Ostano, Paola, Cario-André, Muriel, Calpini, Valérie, Guinea-Viniegra, Juan, Albinger-Hegyi, Andrea, Hoetzenecker, Wolfram, Kolfschoten, Ingrid, Wagner, Erwin F, Werner, Sabine, Dotto, Gian Paolo
Gepubliceerd in 2013

miR-181a decelerates proliferation in cutaneous squamous cell carcinoma by targeting the proto-oncogene KRAS

door Neu, Johannes, Dziunycz, Piotr Jan, Dzung, Andreas, Lefort, Karine, Falke, Martin, Denzler, Rémy, Freiberger, Sandra Nicole, Iotzova-Weiss, Guergana, Kuzmanov, Aleksandar, Levesque, Mitchell Paul, Dotto, Gian-Paolo, Hofbauer, Günther Franz L.
Gepubliceerd in PLoS One (2017)

IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes

door Restivo, Gaetana, Nguyen, Bach-Cuc, Dziunycz, Piotr, Ristorcelli, Elodie, Ryan, Russell J H, Özuysal, Özden Yalçin, Di Piazza, Matteo, Radtke, Freddy, Dixon, Michael J, Hofbauer, Günther F L, Lefort, Karine, Dotto, G Paolo
Gepubliceerd in 2011

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

door Nguyen, Bach-Cuc, Lefort, Karine, Mandinova, Anna, Antonini, Dario, Devgan, Vikram, Della Gatta, Giusy, Koster, Maranke I., Zhang, Zhuo, Wang, Jian, di Vignano, Alice Tommasi, Kitajewski, Jan, Chiorino, Giovanna, Roop, Dennis R., Missero, Caterina, Dotto, G. Paolo
Gepubliceerd in 2006

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

door Procopio, Maria-Giuseppina, Laszlo, Csaba, Labban, Dania Al, Kim, Dong Eun, Bordignon, Pino, Jo, Seunghee, Goruppi, Sandro, Menietti, Elena, Ostano, Paola, Ala, Ugo, Provero, Paolo, Hoetzenecker, Wolfram, Neel, Victor, Kilarski, Witek, Swartz, Melody A., Brisken, Cathrin, Lefort, Karine, Dotto, G. Paolo
Gepubliceerd in Nat Cell Biol (2015)