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Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism
Wnt and Notch signaling have long been established as strongly oncogenic in the mouse mammary gland. Aberrant expression of several Wnts and other components of this pathway in human breast carcinomas has been reported, but evidence for a causative role in the human disease has been missing. Here we...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
National Academy of Sciences
2006
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450156/ https://ncbi.nlm.nih.gov/pubmed/16501043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600065103 |
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