miR-34a/SIRT6 in squamous differentiation and cancer

Por Dotto, G Paolo, Lefort, Karine
Publicado em 2014

The Retinoid-Related Orphan Receptor RORα Promotes Keratinocyte Differentiation via FOXN1

Por Dai, Jun, Brooks, Yang, Lefort, Karine, Getsios, Spiro, Dotto, G. Paolo
Publicado em 2013

Silencing of ASC in Cutaneous Squamous Cell Carcinoma

Por Meier, Katharina, Drexler, Stefan K., Eberle, Franziska C., Lefort, Karine, Yazdi, Amir S.
Publicado no PLoS One (2016)

Negative control of CSL gene transcription by stress/DNA damage response and p53

Por Menietti, Elena, Xu, Xiaoying, Ostano, Paola, Joseph, Jean-Marc, Lefort, Karine, Dotto, G. Paolo
Publicado no Cell Cycle (2016)

Impact of normalization on miRNA microarray expression profiling

Por Pradervand, Sylvain, Weber, Johann, Thomas, Jérôme, Bueno, Manuel, Wirapati, Pratyaksha, Lefort, Karine, Dotto, G. Paolo, Harshman, Keith
Publicado em 2009

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer

Por Lefort, Karine, Ostano, Gian Paola, Mello-Grand, Maurizia, Calpini, Valérie, Scatolini, Maria, Farsetti, Antonella, Dotto, Gian Paolo, Chiorino, Giovanna
Publicado no Oncotarget (2016)

Calcineurin and ATF3: opposite roles in squamous skin cancer

Por Wu, Xunwei, Nguyen, Bach-Cuc, Dziunycz, Piotr, Chang, Sungeun, Brooks, Yang, Lefort, Karine, Hofbauer, Günther F.L., Dotto, G. Paolo
Publicado em 2010

The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response

Por Mandinova, Anna, Lefort, Karine, di Vignano, Alice Tommasi, Stonely, Wesley, Ostano, Paola, Chiorino, Giovanna, Iwaki, Haruhi, Nakanishi, Jotaro, Dotto, G Paolo
Publicado em 2008

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

Por Ayyanan, Ayyakannu, Civenni, Gianluca, Ciarloni, Laura, Morel, Catherine, Mueller, Nathalie, Lefort, Karine, Mandinova, Anna, Raffoul, Wassim, Fiche, Maryse, Dotto, Gian Paolo, Brisken, Cathrin
Publicado em 2006

EGFR signaling as a negative regulator of Notch1 gene expression : a differentiation/apoptosis control mechanism for proliferating keratinocytes and cancer cells

Por Kolev, Vihren, Mandinova, Anna, Guinea-Viniegra, Juan, Hu, Bing, Lefort, Karine, Lambertini, Chiara, Neel, Victor, Dummer, Reinhard, Wagner, Erwin F., Dotto, G. Paolo
Publicado em 2008

CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma

Por Dziunycz, Piotr J., Neu, Johannes, Lefort, Karine, Djerbi, Nadia, Freiberger, Sandra N., Iotzova-Weiss, Guergana, French, Lars E., Dotto, Gian-Paolo, Hofbauer, Günther F.
Publicado no PLoS One (2017)

Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis

Por Hu, Bing, Lefort, Karine, Qiu, Wenying, Nguyen, Bach-Cuc, Rajaram, Renuga Devi, Castillo, Einar, He, Fenglei, Chen, Yiping, Angel, Peter, Brisken, Cathrin, Dotto, G. Paolo
Publicado em 2010

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer

Por Brooks, Yang Sui, Ostano, Paola, Jo, Seung-Hee, Dai, Jun, Getsios, Spiro, Dziunycz, Piotr, Hofbauer, Günther F.L., Cerveny, Kara, Chiorino, Giovanna, Lefort, Karine, Dotto, G. Paolo
Publicado em 2014

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases

Por Lefort, Karine, Mandinova, Anna, Ostano, Paola, Kolev, Vihren, Calpini, Valerie, Kolfschoten, Ingrid, Devgan, Vikram, Lieb, Jocelyn, Raffoul, Wassim, Hohl, Daniel, Neel, Victor, Garlick, Jonathan, Chiorino, Giovanna, Dotto, G. Paolo
Publicado em 2007

A miR-34a-SIRT6 axis in the squamous cell differentiation network

Por Lefort, Karine, Brooks, Yang, Ostano, Paola, Cario-André, Muriel, Calpini, Valérie, Guinea-Viniegra, Juan, Albinger-Hegyi, Andrea, Hoetzenecker, Wolfram, Kolfschoten, Ingrid, Wagner, Erwin F, Werner, Sabine, Dotto, Gian Paolo
Publicado em 2013

miR-181a decelerates proliferation in cutaneous squamous cell carcinoma by targeting the proto-oncogene KRAS

Por Neu, Johannes, Dziunycz, Piotr Jan, Dzung, Andreas, Lefort, Karine, Falke, Martin, Denzler, Rémy, Freiberger, Sandra Nicole, Iotzova-Weiss, Guergana, Kuzmanov, Aleksandar, Levesque, Mitchell Paul, Dotto, Gian-Paolo, Hofbauer, Günther Franz L.
Publicado no PLoS One (2017)

IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes

Por Restivo, Gaetana, Nguyen, Bach-Cuc, Dziunycz, Piotr, Ristorcelli, Elodie, Ryan, Russell J H, Özuysal, Özden Yalçin, Di Piazza, Matteo, Radtke, Freddy, Dixon, Michael J, Hofbauer, Günther F L, Lefort, Karine, Dotto, G Paolo
Publicado em 2011

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

Por Nguyen, Bach-Cuc, Lefort, Karine, Mandinova, Anna, Antonini, Dario, Devgan, Vikram, Della Gatta, Giusy, Koster, Maranke I., Zhang, Zhuo, Wang, Jian, di Vignano, Alice Tommasi, Kitajewski, Jan, Chiorino, Giovanna, Roop, Dennis R., Missero, Caterina, Dotto, G. Paolo
Publicado em 2006

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

Por Procopio, Maria-Giuseppina, Laszlo, Csaba, Labban, Dania Al, Kim, Dong Eun, Bordignon, Pino, Jo, Seunghee, Goruppi, Sandro, Menietti, Elena, Ostano, Paola, Ala, Ugo, Provero, Paolo, Hoetzenecker, Wolfram, Neel, Victor, Kilarski, Witek, Swartz, Melody A., Brisken, Cathrin, Lefort, Karine, Dotto, G. Paolo
Publicado no Nat Cell Biol (2015)