Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer

Downmodulation or loss-of-function mutations of the gene encoding NOTCH1 are associated with dysfunctional squamous cell differentiation and development of squamous cell carcinoma (SCC) in skin and internal organs. While NOTCH1 receptor activation has been well characterized, little is known about h...

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Detalhes bibliográficos
Main Authors: Brooks, Yang Sui, Ostano, Paola, Jo, Seung-Hee, Dai, Jun, Getsios, Spiro, Dziunycz, Piotr, Hofbauer, Günther F.L., Cerveny, Kara, Chiorino, Giovanna, Lefort, Karine, Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002597/
https://ncbi.nlm.nih.gov/pubmed/24743148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72718
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