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Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer
Downmodulation or loss-of-function mutations of the gene encoding NOTCH1 are associated with dysfunctional squamous cell differentiation and development of squamous cell carcinoma (SCC) in skin and internal organs. While NOTCH1 receptor activation has been well characterized, little is known about h...
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Główni autorzy: | , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Clinical Investigation
2014
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002597/ https://ncbi.nlm.nih.gov/pubmed/24743148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72718 |
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