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Silencing of ASC in Cutaneous Squamous Cell Carcinoma

Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an important adaptor protein for inflammasome activation, mediating the secretion of protumorigenic innate cytokines. However, ASC is also known to trigger apoptosis in tumor cells, acting as a tumor-suppressor...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Meier, Katharina, Drexler, Stefan K., Eberle, Franziska C., Lefort, Karine, Yazdi, Amir S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074456/
https://ncbi.nlm.nih.gov/pubmed/27768771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164742
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