טוען...
The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response
Notch signalling has an important role in skin homeostasis, promoting keratinocyte differentiation and suppressing tumorigenesis. Here we show that this pathway also has an essential anti-apoptotic function in the keratinocyte UVB response. Notch1 expression and activity are significantly induced, i...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367396/ https://ncbi.nlm.nih.gov/pubmed/18388864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.45 |
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