Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

par Zhang, Lei, Dong, Xiao, Lee, Moonsook, Maslov, Alexander Y., Wang, Tao, Vijg, Jan
Publié dans Proc Natl Acad Sci U S A (2019)

Myc-Dependent Genome Instability and Lifespan in Drosophila

par Greer, Christina, Lee, Moonsook, Westerhof, Maaike, Milholland, Brandon, Spokony, Rebecca, Vijg, Jan, Secombe, Julie
Publié 2013

Accurate identification of single nucleotide variants in whole genome amplified single cells

par Dong, Xiao, Zhang, Lei, Milholland, Brandon, Lee, Moonsook, Maslov, Alexander Y., Wang, Tao, Vijg, Jan
Publié dans Nat Methods (2017)

Bleomycin-induced genome structural variations in normal, non-tumor cells

par Quispe-Tintaya, Wilber, Lee, Moonsook, Dong, Xiao, Weiser, Daniel A., Vijg, Jan, Maslov, Alexander Y.
Publié dans Sci Rep (2018)

FOXO3a acts to suppress DNA double‐strand break‐induced mutations

par White, Ryan R., Maslov, Alexander Y., Lee, Moonsook, Wilner, Samantha E., Levy, Matthew, Vijg, Jan
Publié dans Aging Cell (2020)

Quantitative detection of low-abundance somatic structural variants in normal cells by high throughput sequencing

par Quispe-Tintaya, Wilber, Gorbacheva, Tatyana, Lee, Moonsook, Makhortov, Sergei, Popov, Vasily N., Vijg, Jan, Maslov, Alexander Y.
Publié dans Nat Methods (2016)

5-Aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1

par Maslov, Alexander Y., Lee, Moonsook, Gundry, Michael, Gravina, Silvia, Strogonova, Nadezhda, Tazearslan, Cagdas, Bendebury, Anastasia, Suh, Yousin, Vijg, Jan
Publié 2012

A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice

par Hiroi, Noboru, Zhu, Hongwen, Lee, MoonSook, Funke, Birgit, Arai, Makoto, Itokawa, Masanari, Kucherlapati, Raju, Morrow, Bernice, Sawamura, Takehito, Agatsuma, Soh
Publié 2005

Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila

par Garcia, Ana Maria, Salomon, Robert N, Witsell, Alice, Liepkalns, Justine, Calder, R Brent, Lee, Moonsook, Lundell, Martha, Vijg, Jan, McVey, Mitch
Publié 2011

Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung

par Dong, Xiao, Shi, Miao, Lee, Moonsook, Toro, Rafael, Gravina, Silvia, Han, Weiguo, Yasuda, Shoya, Wang, Tao, Zhang, Zhengdong, Vijg, Jan, Suh, Yousin, Spivack, Simon D.
Publié dans Epigenetics (2018)

A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses

par Andriani, Grasiella A., Maggi, Elaine, Piqué, Daniel, Zimmerman, Samuel E., Lee, Moonsook, Quispe-Tintaya, Wilber, Maslov, Alexander, Campisi, Judith, Vijg, Jan, Mar, Jessica C., Montagna, Cristina
Publié dans Sci Rep (2019)

Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice

par Suzuki, Go, Harper, Kathryn M., Hiramoto, Takeshi, Sawamura, Takehito, Lee, MoonSook, Kang, Gina, Tanigaki, Kenji, Buell, Mahalah, Geyer, Mark A., Trimble, William S., Agatsuma, Soh, Hiroi, Noboru
Publié 2009

Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice

par Suzuki, Go, Harper, Kathryn M., Hiramoto, Takeshi, Funke, Birgit, Lee, MoonSook, Kang, Gina, Buell, Mahalah, Geyer, Mark A., Kucherlapati, Raju, Morrow, Bernice, Männistö, Pekka T., Agatsuma, Soh, Hiroi, Noboru
Publié 2009

The Progeroid Phenotype of Ku80 Deficiency Is Dominant over DNA-PK(CS) Deficiency

par Reiling, Erwin, Dollé, Martijn E. T., Youssef, Sameh A., Lee, Moonsook, Nagarajah, Bhawani, Roodbergen, Marianne, de With, Piet, de Bruin, Alain, Hoeijmakers, Jan H., Vijg, Jan, van Steeg, Harry, Hasty, Paul
Publié 2014

Deletion of Individual Ku Subunits in Mice Causes an NHEJ-Independent Phenotype Potentially by Altering Apurinic/Apyrimidinic Site Repair

par Choi, Yong Jun, Li, Han, Son, Mi Young, Wang, Xiao-hong, Fornsaglio, Jamie L., Sobol, Robert W., Lee, Moonsook, Vijg, Jan, Imholz, Sandra, Dollé, Martijn E. T., van Steeg, Harry, Reiling, Erwin, Hasty, Paul
Publié 2014