Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

Por Zhang, Lei, Dong, Xiao, Lee, Moonsook, Maslov, Alexander Y., Wang, Tao, Vijg, Jan
Publicado no Proc Natl Acad Sci U S A (2019)

Myc-Dependent Genome Instability and Lifespan in Drosophila

Por Greer, Christina, Lee, Moonsook, Westerhof, Maaike, Milholland, Brandon, Spokony, Rebecca, Vijg, Jan, Secombe, Julie
Publicado em 2013

Accurate identification of single nucleotide variants in whole genome amplified single cells

Por Dong, Xiao, Zhang, Lei, Milholland, Brandon, Lee, Moonsook, Maslov, Alexander Y., Wang, Tao, Vijg, Jan
Publicado no Nat Methods (2017)

Bleomycin-induced genome structural variations in normal, non-tumor cells

Por Quispe-Tintaya, Wilber, Lee, Moonsook, Dong, Xiao, Weiser, Daniel A., Vijg, Jan, Maslov, Alexander Y.
Publicado no Sci Rep (2018)

FOXO3a acts to suppress DNA double‐strand break‐induced mutations

Por White, Ryan R., Maslov, Alexander Y., Lee, Moonsook, Wilner, Samantha E., Levy, Matthew, Vijg, Jan
Publicado no Aging Cell (2020)

Quantitative detection of low-abundance somatic structural variants in normal cells by high throughput sequencing

Por Quispe-Tintaya, Wilber, Gorbacheva, Tatyana, Lee, Moonsook, Makhortov, Sergei, Popov, Vasily N., Vijg, Jan, Maslov, Alexander Y.
Publicado no Nat Methods (2016)

5-Aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1

Por Maslov, Alexander Y., Lee, Moonsook, Gundry, Michael, Gravina, Silvia, Strogonova, Nadezhda, Tazearslan, Cagdas, Bendebury, Anastasia, Suh, Yousin, Vijg, Jan
Publicado em 2012

A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice

Por Hiroi, Noboru, Zhu, Hongwen, Lee, MoonSook, Funke, Birgit, Arai, Makoto, Itokawa, Masanari, Kucherlapati, Raju, Morrow, Bernice, Sawamura, Takehito, Agatsuma, Soh
Publicado em 2005

Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila

Por Garcia, Ana Maria, Salomon, Robert N, Witsell, Alice, Liepkalns, Justine, Calder, R Brent, Lee, Moonsook, Lundell, Martha, Vijg, Jan, McVey, Mitch
Publicado em 2011

Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung

Por Dong, Xiao, Shi, Miao, Lee, Moonsook, Toro, Rafael, Gravina, Silvia, Han, Weiguo, Yasuda, Shoya, Wang, Tao, Zhang, Zhengdong, Vijg, Jan, Suh, Yousin, Spivack, Simon D.
Publicado no Epigenetics (2018)

A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses

Por Andriani, Grasiella A., Maggi, Elaine, Piqué, Daniel, Zimmerman, Samuel E., Lee, Moonsook, Quispe-Tintaya, Wilber, Maslov, Alexander, Campisi, Judith, Vijg, Jan, Mar, Jessica C., Montagna, Cristina
Publicado no Sci Rep (2019)

Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice

Por Suzuki, Go, Harper, Kathryn M., Hiramoto, Takeshi, Sawamura, Takehito, Lee, MoonSook, Kang, Gina, Tanigaki, Kenji, Buell, Mahalah, Geyer, Mark A., Trimble, William S., Agatsuma, Soh, Hiroi, Noboru
Publicado em 2009

Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice

Por Suzuki, Go, Harper, Kathryn M., Hiramoto, Takeshi, Funke, Birgit, Lee, MoonSook, Kang, Gina, Buell, Mahalah, Geyer, Mark A., Kucherlapati, Raju, Morrow, Bernice, Männistö, Pekka T., Agatsuma, Soh, Hiroi, Noboru
Publicado em 2009

The Progeroid Phenotype of Ku80 Deficiency Is Dominant over DNA-PK(CS) Deficiency

Por Reiling, Erwin, Dollé, Martijn E. T., Youssef, Sameh A., Lee, Moonsook, Nagarajah, Bhawani, Roodbergen, Marianne, de With, Piet, de Bruin, Alain, Hoeijmakers, Jan H., Vijg, Jan, van Steeg, Harry, Hasty, Paul
Publicado em 2014

Deletion of Individual Ku Subunits in Mice Causes an NHEJ-Independent Phenotype Potentially by Altering Apurinic/Apyrimidinic Site Repair

Por Choi, Yong Jun, Li, Han, Son, Mi Young, Wang, Xiao-hong, Fornsaglio, Jamie L., Sobol, Robert W., Lee, Moonsook, Vijg, Jan, Imholz, Sandra, Dollé, Martijn E. T., van Steeg, Harry, Reiling, Erwin, Hasty, Paul
Publicado em 2014