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Myc-Dependent Genome Instability and Lifespan in Drosophila
The Myc family of transcription factors are key regulators of cell growth and proliferation that are dysregulated in a large number of human cancers. When overexpressed, Myc family proteins also cause genomic instability, a hallmark of both transformed and aging cells. Using an in vivo lacZ mutation...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765364/ https://ncbi.nlm.nih.gov/pubmed/24040302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074641 |
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