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Mutation and catastrophe in the aging genome
In the 1960s, Leslie Orgel proposed what is now known as the error catastrophe theory of aging, arguing that errors in protein translation that reduce the fidelity of the protein-translating enzymes would lead to a feedback loop of increasingly inaccurate protein synthesis, terminating in the death...
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| Publicado no: | Exp Gerontol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480213/ https://ncbi.nlm.nih.gov/pubmed/28263867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.02.073 |
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