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Differences between germline and somatic mutation rates in humans and mice

The germline mutation rate has been extensively studied and has been found to vary greatly between species, but much less is known about the somatic mutation rate in multicellular organisms, which remains very difficult to determine. Here, we present data on somatic mutation rates in mice and humans...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Milholland, Brandon, Dong, Xiao, Zhang, Lei, Hao, Xiaoxiao, Suh, Yousin, Vijg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436103/
https://ncbi.nlm.nih.gov/pubmed/28485371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15183
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