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Mutation and catastrophe in the aging genome

In the 1960s, Leslie Orgel proposed what is now known as the error catastrophe theory of aging, arguing that errors in protein translation that reduce the fidelity of the protein-translating enzymes would lead to a feedback loop of increasingly inaccurate protein synthesis, terminating in the death...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Gerontol
Egile Nagusiak: Milholland, Brandon, Suh, Yousin, Vijg, Jan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480213/
https://ncbi.nlm.nih.gov/pubmed/28263867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.02.073
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