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Somatic mutations, genome mosaicism, cancer and aging
Genomes are inherently unstable due to the need for DNA sequence variation in the germ line to fuel evolution through natural selection. In somatic tissues mutations accumulate during development and aging, generating genome mosaics. There is little information about the possible causal role of incr...
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| Publicado no: | Curr Opin Genet Dev |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480293/ https://ncbi.nlm.nih.gov/pubmed/25282114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.04.002 |
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