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Somatic mutations, genome mosaicism, cancer and aging
Genomes are inherently unstable due to the need for DNA sequence variation in the germ line to fuel evolution through natural selection. In somatic tissues mutations accumulate during development and aging, generating genome mosaics. There is little information about the possible causal role of incr...
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| Wydane w: | Curr Opin Genet Dev |
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| 1. autor: | |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480293/ https://ncbi.nlm.nih.gov/pubmed/25282114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.04.002 |
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