Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice

Duplication of human chromosome 22q11.2 is associated with elevated rates of mental retardation, autism and many other behavioral phenotypes. However, because duplications cover 1.5–6 Mb, the precise manner in which segments of 22q11.2 causally affect behavior is not known in humans. We have now det...

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Detalhes bibliográficos
Main Authors: Suzuki, Go, Harper, Kathryn M., Hiramoto, Takeshi, Funke, Birgit, Lee, MoonSook, Kang, Gina, Buell, Mahalah, Geyer, Mark A., Kucherlapati, Raju, Morrow, Bernice, Männistö, Pekka T., Agatsuma, Soh, Hiroi, Noboru
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748897/
https://ncbi.nlm.nih.gov/pubmed/19617637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp334
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