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Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model

Although twin studies indicate clear genetic bases of autism spectrum disorder (ASD), the precise mechanisms through which genetic variations causally result in ASD are poorly understood. Individuals with 3 Mb and nested 1.5 Mb hemizygosity of the chromosome 22q11.2 represent genetically identifiabl...

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Autores principales: Hiramoto, Takeshi, Kang, Gina, Suzuki, Go, Satoh, Yasushi, Kucherlapati, Raju, Watanabe, Yasuhiro, Hiroi, Noboru
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221538/
https://ncbi.nlm.nih.gov/pubmed/21908517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr404
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