TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres

by Le, Phuong N., Maranon, David G., Altina, Noelia H., Battaglia, Christine L. R., Bailey, Susan M.
Published 2013

Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers

by Gan, Gregory N., Eagles, Justin, Keysar, Stephen B., Wang, Guoliang, Glogowska, Magdalena J., Altunbas, Cem, Anderson, Ryan T., Le, Phuong N., Morton, J. Jason, Frederick, Barbara, Raben, David, Wang, Xiao-Jing, Jimeno, Antonio
Published in Cancer Res (2014)

Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer

by Morton, J. Jason, Keysar, Stephen B., Perrenoud, Loni, Chimed, Tugs-Saikhan, Reisinger, Julie, Jackson, Brian, Le, Phuong N., Nieto, Cera, Gomez, Karina, Miller, Bettina, Gao, Dexiang, Somerset, Hilary, Wang, Xiao-Jing, Jimeno, Antonio
Published in Mol Carcinog (2018)

Wnt signaling dynamics in head and neck squamous cell cancer tumor-stroma interactions

by Le, Phuong N., Keysar, Stephen B., Miller, Bettina, Eagles, Justin R., Chimed, Tugs-Saikhan, Reisinger, Julie, Gomez, Karina E., Nieto, Cera, Jackson, Brian C., Somerset, Hilary L., Morton, J. Jason, Wang, Xiao-Jing, Jimeno, Antonio
Published in Mol Carcinog (2018)

Molecular characterisation of murine acute myeloid leukaemia induced by (56)Fe ion and (137)Cs gamma ray irradiation

by Steffen, Leta S., Bacher, Jeffery W., Peng, Yuanlin, Le, Phuong N., Ding, Liang-Hao, Genik, Paula C., Ray, F. Andrew, Bedford, Joel S., Fallgren, Christina M., Bailey, Susan M., Ullrich, Robert L., Weil, Michael M., Story, Michael D.
Published 2013

Leading Edge or Tumor Core: Intratumor Cancer Stem Cell Niches in Oral Cavity Squamous Cell Carcinoma and their Association with Stem Cell Function

by Chowdhury, Farshad N., Reisinger, Julie, Gomez, Karina E., Chimed, Tugs-Saikhan, Thomas, Carissa M., Le, Phuong N., Miller, Bettina, Morton, John J., Nieto, Cera M., Somerset, Hilary L., Wang, Xiao-Jing, Keysar, Stephen B., Jimeno, Antonio
Published in Oral Oncol (2019)

A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma

by Bowles, Daniel W., Keysar, Stephen B., Eagles, Justin R., Wang, Guoliang, Glogowska, Magdalena J., McDermott, Jessica D., Le, Phuong N., Gao, Dexiang, Ray, Charles E., Rochon, Paul J., Roop, Dennis R., Tan, Aik-Choon, Serracino, Hilary S., Jimeno, Antonio
Published in Oral Oncol (2015)

Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells

by Gomez, Karina E., Wu, FangLong, Keysar, Stephen B., Morton, J. Jason, Miller, Bettina, Chimed, Tugs-Saikhan, Le, Phuong N., Nieto, Cera, Chowdhury, Farshad N., Tyagi, Anit, Lyons, Traci R., Young, Christian D., Zhou, Hongmei, Somerset, Hilary L., Wang, Xiao-Jing, Jimeno, Antonio
Published in Cancer Res (2020)

Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene events associated with tumor progression

by Keysar, Stephen B., Eagles, Justin R., Miller, Bettina, Jackson, Brian C., Chowdhury, Farshad N., Reisinger, Julie, Chimed, Tugs-Saikhan, Le, Phuong N., Morton, John J., Somerset, Hilary L., Varella-Garcia, Marileila, Tan, Aik-Choon, Song, John I., Bowles, Daniel W., Reyland, Mary E., Jimeno, Antonio
Published in Clin Cancer Res (2018)

Inhibiting translation elongation with SVC112 suppresses cancer stem cells and inhibits growth in head and neck squamous carcinoma

by Keysar, Stephen B., Gomes, Nathan, Miller, Bettina, Jackson, Brian C., Le, Phuong N., Morton, J. Jason, Reisinger, Julie, Chimed, Tugs-Saikhan, Gomez, Karina E., Nieto, Cera, Frederick, Barbara, Pronk, Gijsbertus J., Somerset, Hilary L., Tan, Aik-Choon, Wang, Xiao-Jing, Raben, David, Su, Tin Tin, Jimeno, Antonio
Published in Cancer Res (2020)

Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft.

by Morton, J. Jason, Alzofon, Nathaniel, Keysar, Stephen B., Chimed, Tugs-Saikhan, Reisinger, Julie, Perrenoud, Loni, Le, Phuong N., Nieto, Cera, Gomez, Karina, Miller, Bettina, Yeager, Randi, Gao, Dexiang, Tan, Aik-Choon, Somerset, Hilary, Medina, Theresa, Wang, Xiao-Jing, Wang, Jing H., Robinson, William, Roop, Dennis R., Gonzalez, Rene, Jimeno, Antonio
Published in Mol Cancer Res (2020)

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2

by Keysar, Stephen B., Le, Phuong N., Miller, Bettina, Jackson, Brian C., Eagles, Justin R., Nieto, Cera, Kim, Jihye, Tang, Binwu, Glogowska, Magdalena J., Morton, J. Jason, Padilla-Just, Nuria, Gomez, Karina, Warnock, Emily, Reisinger, Julie, Arcaroli, John J., Messersmith, Wells A., Wakefield, Lalage M., Gao, Dexiang, Tan, Aik-Choon, Serracino, Hilary, Jimeno, Antonio
Published in J Natl Cancer Inst (2016)

Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

by Keysar, Stephen B., Le, Phuong N., Anderson, Ryan T., Morton, J. Jason, Bowles, Daniel W., Paylor, Jeramiah J., Vogler, Brian W., Thorburn, Jackie, Fernandez, Pamela, Glogowska, Magdalena J., Takimoto, Sarah M., Sehrt, Daniel B., Gan, Gregory N., Eagles-Soukup, Justin, Serracino, Hilary, Hirsch, Fred R., Lucia, M. Scott, Thorburn, Andrew, Song, John I., Wang, Xiao-Jing, Jimeno, Antonio
Published 2013

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

by Morton, J. Jason, Bird, Gregory, Keysar, Stephen B., Astling, David P., Lyons, Traci R, Anderson, Ryan T., Glogowska, Magdalena J., Estes, Patricia, Eagles, Justin R., Le, Phuong N., Gan, Gregory, McGettigan, Brett, Fernandez, Pamela, Padilla-Just, Nuria, Varella-Garcia, Marileila, Song, John I., Bowles, Daniel W., Schedin, Pepper, Tan, Aik-Choon, Roop, Dennis R., Wang, Xiao-Jing, Refaeli, Yosef, Jimeno, Antonio
Published in Oncogene (2015)

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins

by Keysar, Stephen B., Astling, David P., Anderson, Ryan T., Vogler, Brian W., Bowles, Daniel W., Morton, J. Jason, Paylor, Jeramiah J., Glogowska, Magdalena J., Le, Phuong N., Eagles-Soukup, Justin R., Kako, Severine L., Takimoto, Sarah M., Sehrt, Daniel B., Umpierrez, Adrian, Pittman, Morgan A., Macfadden, Sarah M., Helber, Ryan M., Peterson, Scott, Hausman, Diana F., Said, Sherif, Leem, Ted H., Goddard, Julie A., Arcaroli, John J., Messersmith, Wells A., Robinson, William A., Hirsch, Fred R., Varella-Garcia, Marileila, Raben, David, Wang, Xiao-Jing, Song, John I., Tan, Aik-Choon, Jimeno, Antonio
Published 2013

Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-X(L) Inhibitor

by Wang, Le, Doherty, George A., Judd, Andrew S., Tao, Zhi-Fu, Hansen, T. Matthew, Frey, Robin R., Song, Xiaohong, Bruncko, Milan, Kunzer, Aaron R., Wang, Xilu, Wendt, Michael D., Flygare, John A., Catron, Nathaniel D., Judge, Russell A., Park, Chang H., Shekhar, Shashank, Phillips, Darren C., Nimmer, Paul, Smith, Morey L., Tahir, Stephen K., Xiao, Yu, Xue, John, Zhang, Haichao, Le, Phuong N., Mitten, Michael J., Boghaert, Erwin R., Gao, Wenqing, Kovar, Peter, Choo, Edna F., Diaz, Dolores, Fairbrother, Wayne J., Elmore, Steven W., Sampath, Deepak, Leverson, Joel D., Souers, Andrew James
Published in ACS Med Chem Lett (2020)