XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

The limitations of cancer cell lines have led to the development of direct patient derived xenograft (PDX) models. However, the interplay between the implanted human cancer cells and recruited mouse stromal and immune cells alters the tumor microenvironment and limits the value of these models. To o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Morton, J. Jason, Bird, Gregory, Keysar, Stephen B., Astling, David P., Lyons, Traci R, Anderson, Ryan T., Glogowska, Magdalena J., Estes, Patricia, Eagles, Justin R., Le, Phuong N., Gan, Gregory, McGettigan, Brett, Fernandez, Pamela, Padilla-Just, Nuria, Varella-Garcia, Marileila, Song, John I., Bowles, Daniel W., Schedin, Pepper, Tan, Aik-Choon, Roop, Dennis R., Wang, Xiao-Jing, Refaeli, Yosef, Jimeno, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613815/
https://ncbi.nlm.nih.gov/pubmed/25893296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.94
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados