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Humanized mouse xenograft models: narrowing the tumor-microenvironment gap

Cancer research has long been hampered by the limitations of the current model systems. Both cultured cells and mouse xenografts grow in an environment highly dissimilar to that of their originating tumor, frequently resulting in promising treatments that are ultimately clinically ineffective. The d...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Morton, J. Jason, Bird, Gregory, Refaeli, Yosef, Jimeno, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093075/
https://ncbi.nlm.nih.gov/pubmed/27587540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1260
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