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Humanized mouse xenograft models: narrowing the tumor-microenvironment gap

Cancer research has long been hampered by the limitations of the current model systems. Both cultured cells and mouse xenografts grow in an environment highly dissimilar to that of their originating tumor, frequently resulting in promising treatments that are ultimately clinically ineffective. The d...

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Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Morton, J. Jason, Bird, Gregory, Refaeli, Yosef, Jimeno, Antonio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093075/
https://ncbi.nlm.nih.gov/pubmed/27587540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1260
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