Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

The epidermal growth factor receptor (EGFR)-directed monoclonal antibody cetuximab is the only targeted therapy approved for the treatment of head and neck squamous cell carcinoma (HNSCC), but is only effective in a minority of patients. Epithelial-to-mesenchymal transition (EMT) has been implicated...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Keysar, Stephen B., Le, Phuong N., Anderson, Ryan T., Morton, J. Jason, Bowles, Daniel W., Paylor, Jeramiah J., Vogler, Brian W., Thorburn, Jackie, Fernandez, Pamela, Glogowska, Magdalena J., Takimoto, Sarah M., Sehrt, Daniel B., Gan, Gregory N., Eagles-Soukup, Justin, Serracino, Hilary, Hirsch, Fred R., Lucia, M. Scott, Thorburn, Andrew, Song, John I., Wang, Xiao-Jing, Jimeno, Antonio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674118/
https://ncbi.nlm.nih.gov/pubmed/23576557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4047
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller