Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells

Tumor-associated macrophages (TAM) in the tumor microenvironment (TME) cooperate with cancer stem cells (CSC) to maintain stemness. We recently identified CD44 as a surface marker defining head and neck squamous cell carcinoma (HNSCC) CSC. PI3K-4EBP1-SOX2 activation and signaling regulate CSC proper...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cancer Res
Huvudupphovsmän: Gomez, Karina E., Wu, FangLong, Keysar, Stephen B., Morton, J. Jason, Miller, Bettina, Chimed, Tugs-Saikhan, Le, Phuong N., Nieto, Cera, Chowdhury, Farshad N., Tyagi, Anit, Lyons, Traci R., Young, Christian D., Zhou, Hongmei, Somerset, Hilary L., Wang, Xiao-Jing, Jimeno, Antonio
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146866/
https://ncbi.nlm.nih.gov/pubmed/32816856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1079
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk