Global Fit Analysis of Glucose Binding Curves Reveals a Minimal Model for Kinetic Cooperativity in Human Glucokinase

Por Larion, Mioara, Miller, Brian G.
Publicado em 2010

Homotropic Allosteric Regulation in Monomeric Mammalian Glucokinase

Por Larion, Mioara, Miller, Brian G.
Publicado em 2011

Conformational heterogeneity and intrinsic disorder in enzyme regulation: Glucokinase as a case study

Por Larion, Mioara, Miller, Brian, Brüschweiler, Rafael
Publicado no Intrinsically Disord Proteins (2015)

DRES-18. SUMO1 AND VALOSIN-CONTAINING PROTEIN REGULATE RETINOID RECEPTOR PROTEIN TURNOVER– A PROCESS DISRUPTED IN GLIOBLASTOMA

Por Rodriguez, Virginia, Bailey, Rolanda, Larion, Mioara, Gilbert, Mark
Publicado no Neuro Oncol (2018)

Retinoid receptor turnover mediated by sumoylation, ubiquitination and the valosin-containing protein is disrupted in glioblastoma

Por Rodriguez, Virginia, Bailey, Rolanda, Larion, Mioara, Gilbert, Mark R.
Publicado no Sci Rep (2019)

CBMT-43. SINGLE LIVE TUMOR CELL METABOLISM VIA RAMAN IMAGING MICROSCOPY

Por Lita, Adrian, Wu, Jing, Park, Deric, Gilbert, Mark, Larion, Mioara
Publicado no Neuro Oncol (2018)

CBMT-07. BIOMARKERS OF AGGRESSIVENESS IN IDH MUTANT GLIOMA

Por Yamasaki, Tomohiro, Lita, Adrian, Dowdy, Tyrone, Gilbert, Mark, Larion, Mioara
Publicado no Neuro Oncol (2019)

BCAbox Algorithm Expands Capabilities of Raman Microscope for Single Organelles Assessment

Por Kuzmin, Andrey N., Pliss, Artem, Rzhevskii, Alex, Lita, Adrian, Larion, Mioara
Publicado no Biosensors (Basel) (2018)

Direct Evidence for Conformational Heterogeneity in Human Pancreatic Glucokinase from High-Resolution NMR

Por Larion, Mioara, Salinas, Roberto K., Bruschweiler-Li, Lei, Brüschweiler, Rafael, Miller, Brian G.
Publicado em 2010

Order–Disorder Transitions Govern Kinetic Cooperativity and Allostery of Monomeric Human Glucokinase

Por Larion, Mioara, Salinas, Roberto Kopke, Bruschweiler-Li, Lei, Miller, Brian G., Brüschweiler, Rafael
Publicado em 2012

Role of connecting loop I in catalysis and allosteric regulation of human glucokinase

Por Martinez, Juliana A, Larion, Mioara, Conejo, Maria S, Porter, Carol M, Miller, Brian G
Publicado em 2014

CBMT-44. METABOLIC PLASTICITY AND HETEROGENEITY IN IDH1(MUT) CELL LINES PRODUCES RESISTANCE TO GLUTAMINASE INHIBITION BY CB839

Por Ruiz Rodado, Victor, Lita, Adrian, Dowdy, Tyrone, Saldana, Alejandra Cavazos, Gilbert, Mark, Larion, Mioara
Publicado no Neuro Oncol (2018)

Magnetic resonance spectroscopy for the study of cns malignancies

Por Ruiz-Rodado, Victor, Brender, Jeffery R., Cherukuri, Murali K., Gilbert, Mark R., Larion, Mioara
Publicado no Prog Nucl Magn Reson Spectrosc (2020)

Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism

Por Yu, Di, Liu, Yang, Zhou, Yiqiang, Ruiz-Rodado, Victor, Larion, Mioara, Xu, Guowang, Yang, Chunzhang
Publicado no Proc Natl Acad Sci U S A (2020)

Dual allosteric activation mechanisms in monomeric human glucokinase

Por Whittington, A. Carl, Larion, Mioara, Bowler, Joseph M., Ramsey, Kristen M., Brüschweiler, Rafael, Miller, Brian G.
Publicado no Proc Natl Acad Sci U S A (2015)

EXTH-58. ONC206, AN IMIPRIDONE FAMILY MEMBER, SUPPRESSES GLIOBLASTOMA CELLS VIA BLOCKING CANCER STEMNESS PATHWAYS

Por Jung, Jinkyu, Dowdy, Tyrone, Tabouret, Emeline, Reynolds, Brent, Allen, Joshua, Larion, Mioara, Gilbert, Mark, Park, Deric
Publicado no Neuro Oncol (2018)

Millisecond Dynamics of the Small Domain Generate the Kinetic Cooperativity Effect in Human Pancreatic Glucokinase

Por Larion, Mioara, Hansen, Alexandar L., Zhang, Fengli, Bruschweiler-Li, Lei, Tugarinov, Vitali, Miller, Brian G., Brüschweiler, Rafael
Publicado no Angew Chem Int Ed Engl (2015)

METB-04. METABOLIC EFFECTS OF A GLUTAMINASE INHIBITOR ON GLIOMA CELL LINES

Por Rodado, Victor Ruiz, Saldana, Alejandra Cavazos, Movva, Sriya, Lita, Adrian, Dowdy, Tyrone, Gilbert, Mark R, Larion, Mioara
Publicado no Neuro Oncol (2017)

Hypoxia in the glioblastoma microenvironment: shaping the phenotype of cancer stem-like cells

Por Colwell, Nicole, Larion, Mioara, Giles, Amber J., Seldomridge, Ashlee N., Sizdahkhani, Saman, Gilbert, Mark R., Park, Deric M.
Publicado no Neuro Oncol (2017)

IDH mutation in glioma: molecular mechanisms and potential therapeutic targets

Por Han, Sue, Liu, Yang, Cai, Sabrina J., Qian, Mingyu, Ding, Jianyi, Larion, Mioara, Gilbert, Mark R., Yang, Chunzhang
Publicado no Br J Cancer (2020)