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Conformational heterogeneity and intrinsic disorder in enzyme regulation: Glucokinase as a case study

Many human proteins are predicted to contain intrinsically disordered regions (IDRs), yet their occurrence in enzymes is notably rare. Human pancreatic glucokinase (GCK) is one of a small, but growing number of enzymes shown to possess an IDR. In this commentary, we summarize the results of recent b...

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Detalhes bibliográficos
Publicado no:Intrinsically Disord Proteins
Main Authors: Larion, Mioara, Miller, Brian, Brüschweiler, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314934/
https://ncbi.nlm.nih.gov/pubmed/28232887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21690707.2015.1011008
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