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Order–Disorder Transitions Govern Kinetic Cooperativity and Allostery of Monomeric Human Glucokinase

Glucokinase (GCK) catalyzes the rate-limiting step of glucose catabolism in the pancreas, where it functions as the body's principal glucose sensor. GCK dysfunction leads to several potentially fatal diseases including maturity–onset diabetes of the young type II (MODY-II) and persistent hypogl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Larion, Mioara, Salinas, Roberto Kopke, Bruschweiler-Li, Lei, Miller, Brian G., Brüschweiler, Rafael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525530/
https://ncbi.nlm.nih.gov/pubmed/23271955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001452
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