Extent of Cross-Resistance between Agents Used To Treat Human Immunodeficiency Virus Type 1 Infection in Clinically Derived Isolates

Por Harrigan, P. Richard, Larder, Brendan A.
Publicado em 2002

Biochemical Mechanism of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Resistance to Stavudine

Por Lennerstrand, Johan, Stammers, David K., Larder, Brendan A.
Publicado em 2001

Relative Replicative Fitness of Zidovudine-Resistant Human Immunodeficiency Virus Type 1 Isolates In Vitro

Por Harrigan, P. Richard, Bloor, Stuart, Larder, Brendan A.
Publicado em 1998

Correlation between Viral Resistance to Zidovudine and Resistance at the Reverse Transcriptase Level for a Panel of Human Immunodeficiency Virus Type 1 Mutants

Por Lennerstrand, Johan, Hertogs, Kurt, Stammers, David K., Larder, Brendan A.
Publicado em 2001

Correlation of Phenotypic Zidovudine Resistance with Mutational Patterns in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1: Interpretation of Established Mutation...

Por Stürmer, Martin, Staszewski, Schlomo, Doerr, Hans-Wilhelm, Larder, Brendan, Bloor, Stuart, Hertogs, Kurt
Publicado em 2003

Effects of Dipeptide Insertions between Codons 69 and 70 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on Primer Unblocking, Deoxynucleoside Triphosphate Inhibition,...

Por Meyer, Peter R., Lennerstrand, Johan, Matsuura, Suzanne E., Larder, Brendan A., Scott, Walter A.
Publicado em 2003

A Novel Polymorphism at Codon 333 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Can Facilitate Dual Resistance to Zidovudine and l-2′,3′-Dideoxy-3′-Thiacytidine...

Por Kemp, Sharon D., Shi, Chaofu, Bloor, Stuart, Harrigan, P. Richard, Mellors, John W., Larder, Brendan A.
Publicado em 1998

Potential Impact of a Free Online HIV Treatment Response Prediction System for Reducing Virological Failures and Drug Costs after Antiretroviral Therapy Failure in a Resource-Limit...

Por Revell, Andrew D., Alvarez-Uria, Gerardo, Wang, Dechao, Pozniak, Anton, Montaner, Julio S., Lane, H. Clifford, Larder, Brendan A.
Publicado em 2013

The use of computational models to predict response to HIV therapy for clinical cases in Romania

Por Revell, Andrew D, Ene, Luminiţa, Duiculescu, Dan, Wang, Dechao, Youle, Mike, Pozniak, Anton, Montaner, Julio, Larder, Brendan A
Publicado em 2012

A Mutation in the 3′ Region of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase (Y318F) Associated with Nonnucleoside Reverse Transcriptase Inhibitor Resistance

Por Harrigan, P. Richard, Salim, Mahboob, Stammers, David K., Wynhoven, Brian, Brumme, Zabrina L., McKenna, Paula, Larder, Brendan, Kemp, S. D.
Publicado em 2002

Comparative Analysis of Two Commercial Phenotypic Assays for Drug Susceptibility Testing of Human Immunodeficiency Virus Type 1

Por Qari, Shoukat H., Respess, Richard, Weinstock, Hillard, Beltrami, Elise M., Hertogs, Kurt, Larder, Brendan A., Petropoulos, Christos J., Hellmann, Nicholas, Heneine, Walid
Publicado em 2002

Resistance to Nucleoside Analog Reverse Transcriptase Inhibitors Mediated by Human Immunodeficiency Virus Type 1 p6 Protein

Por Peters, Solange, Muñoz, Miguel, Yerly, Sabine, Sanchez-Merino, Victor, Lopez-Galindez, Cecilio, Perrin, Luc, Larder, Brendan, Cmarko, Dusan, Fakan, Stanislav, Meylan, Pascal, Telenti, Amalio
Publicado em 2001

3′-Azido-3′-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes

Por Ren, Jingshan, Esnouf, Robert M., Hopkins, Andrew L., Jones, E. Yvonne, Kirby, Ian, Keeling, James, Ross, Carl K., Larder, Brendan A., Stuart, David I., Stammers, David K.
Publicado em 1998

Performance of the Affymetrix GeneChip HIV PRT 440 Platform for Antiretroviral Drug Resistance Genotyping of Human Immunodeficiency Virus Type 1 Clades and Viral Isolates with Len...

Por Vahey, Maryanne, Nau, Martin E., Barrick, Sandra, Cooley, John D., Sawyer, Robert, Sleeker, Alex A., Vickerman, Peter, Bloor, Stuart, Larder, Brendan, Michael, Nelson L., Wegner, Scott A.
Publicado em 1999

A Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutational Pattern Confers Phenotypic Lamivudine Resistance in the Absence of Mutation 184V

Por Hertogs, Kurt, Bloor, Stuart, De Vroey, Veronique, van den Eynde, Christel, Dehertogh, Pascale, van Cauwenberge, Anja, Stürmer, Martin, Alcorn, Timothy, Wegner, Scott, van Houtte, Margriet, Miller, Veronica, Larder, Brendan A.
Publicado em 2000

Genotypic Correlates of Phenotypic Resistance to Efavirenz in Virus Isolates from Patients Failing Nonnucleoside Reverse Transcriptase Inhibitor Therapy

Por Bacheler, Lee, Jeffrey, Susan, Hanna, George, D'Aquila, Richard, Wallace, Lany, Logue, Kelly, Cordova, Beverly, Hertogs, Kurt, Larder, Brendan, Buckery, Renay, Baker, David, Gallagher, Karen, Scarnati, Helen, Tritch, Radonna, Rizzo, Chris
Publicado em 2001

An update to the HIV-TRePS system: the development and evaluation of new global and local computational models to predict HIV treatment outcomes, with or without a genotype

Por Revell, Andrew D., Wang, Dechao, Wood, Robin, Morrow, Carl, Tempelman, Hugo, Hamers, Raph L., Reiss, Peter, van Sighem, Ard I., Nelson, Mark, Montaner, Julio S. G., Lane, H. Clifford, Larder, Brendan A.
Publicado no J Antimicrob Chemother (2016)

Interference between D30N and L90M in Selection and Development of Protease Inhibitor-Resistant Human Immunodeficiency Virus Type 1

Por Sugiura, Wataru, Matsuda, Zene, Yokomaku, Yoshiyuki, Hertogs, Kurt, Larder, Brendan, Oishi, Tsuyoshi, Okano, Aiko, Shiino, Teiichirou, Tatsumi, Masashi, Matsuda, Masakazu, Abumi, Hanae, Takata, Noboru, Shirahata, Satoshi, Yamada, Kaneo, Yoshikura, Hiroshi, Nagai, Yoshiyuki
Publicado em 2002

Clinical Evaluation of the Potential Utility of Computational Modeling as an HIV Treatment Selection Tool by Physicians with Considerable HIV Experience

Por Larder, Brendan A., Revell, Andrew, Mican, JoAnn M., Agan, Brian K., Harris, Marianne, Torti, Carlo, Izzo, Ilaria, Metcalf, Julia A., Rivera-Goba, Migdalia, Marconi, Vincent C., Wang, Dechao, Coe, Daniel, Gazzard, Brian, Montaner, Julio, Lane, H. Clifford
Publicado em 2011

A Rapid Method for Simultaneous Detection of Phenotypic Resistance to Inhibitors of Protease and Reverse Transcriptase in Recombinant Human Immunodeficiency Virus Type 1 Isolates f...

Por Hertogs, Kurt, de Béthune, Marie-Pierre, Miller, Veronica, Ivens, Tania, Schel, Patricia, Van Cauwenberge, Anja, Van den Eynde, Christel, van Gerwen, Veerle, Azijn, Hilde, van Houtte, Margriet, Peeters, Frank, Staszewski, Schlomo, Conant, Marcus, Bloor, Stuart, Kemp, Sharon, Larder, Brendan, Pauwels, Rudi
Publicado em 1998