Genotypic Correlates of Phenotypic Resistance to Efavirenz in Virus Isolates from Patients Failing Nonnucleoside Reverse Transcriptase Inhibitor Therapy

Efavirenz (also known as DMP 266 or SUSTIVA) is a potent nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) activity and of HIV-1 replication in vitro and in vivo. Most patients on efavirenz-containing regimens have sustained antiviral responses; howeve...

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Detalhes bibliográficos
Main Authors: Bacheler, Lee, Jeffrey, Susan, Hanna, George, D'Aquila, Richard, Wallace, Lany, Logue, Kelly, Cordova, Beverly, Hertogs, Kurt, Larder, Brendan, Buckery, Renay, Baker, David, Gallagher, Karen, Scarnati, Helen, Tritch, Radonna, Rizzo, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114903/
https://ncbi.nlm.nih.gov/pubmed/11333879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.4999-5008.2001
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