Biochemical Mechanism of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Resistance to Stavudine

We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...

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Detalhes bibliográficos
Main Authors: Lennerstrand, Johan, Stammers, David K., Larder, Brendan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90617/
https://ncbi.nlm.nih.gov/pubmed/11408240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2144-2146.2001
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