Correlation of Phenotypic Zidovudine Resistance with Mutational Patterns in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1: Interpretation of Established Mutations and Characterization of New Polymorphisms at Codons 208, 211, and 214

Zidovudine resistance (ZDV-R) is associated with classic genotypic changes at codons 41, 67, 70, 210, 215, and 219 of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) gene as well as with the multinucleoside resistance (MNR) complexes (Q151M MNR complex; 6-bp insertion/A62V...

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Bibliografiska uppgifter
Huvudupphovsmän: Stürmer, Martin, Staszewski, Schlomo, Doerr, Hans-Wilhelm, Larder, Brendan, Bloor, Stuart, Hertogs, Kurt
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC149009/
https://ncbi.nlm.nih.gov/pubmed/12499169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.54-61.2003
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