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Correlation of Phenotypic Zidovudine Resistance with Mutational Patterns in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1: Interpretation of Established Mutations and Characterization of New Polymorphisms at Codons 208, 211, and 214

Zidovudine resistance (ZDV-R) is associated with classic genotypic changes at codons 41, 67, 70, 210, 215, and 219 of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) gene as well as with the multinucleoside resistance (MNR) complexes (Q151M MNR complex; 6-bp insertion/A62V...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Principais autores: Stürmer, Martin, Staszewski, Schlomo, Doerr, Hans-Wilhelm, Larder, Brendan, Bloor, Stuart, Hertogs, Kurt
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.54-61.2003
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