Biochemical Mechanism of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Resistance to Stavudine

We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Lennerstrand, Johan, Stammers, David K., Larder, Brendan A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90617/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11408240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.7.2144-2146.2001
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