Flow Cytometry-Based Detection and Analysis of BCL-2 Family Proteins and Mitochondrial Outer Membrane Permeabilization (MOMP)

par Ludwig, Lindsey M., Maxcy, Katrina L., LaBelle, James L.
Publié dans Methods Mol Biol (2019)

Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation

par Ludwig, Lindsey M., Nassin, Michele L., Hadji, Abbas, LaBelle, James L.
Publié dans Front Pediatr (2016)

Synthesis and Purification of Homogeneous Lipid-Based Peptide Nanocarriers by Overcoming Phospholipid Ester Hydrolysis

par Schnorenberg, Mathew R., Yoo, Sang Pil, Tirrell, Matthew V., LaBelle, James L.
Publié dans ACS Omega (2018)

Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization

par Ludwig, Lindsey M., Roach, Lauren E., Katz, Samuel G., LaBelle, James L.
Publié dans Apoptosis (2020)

RNA Polymerase tags to monitor multidimensional protein-protein interactions reveal pharmacological engagement of Bcl-2 proteins

par Pu, Jinyue, Dewey, Jeffrey A., Hadji, Abbas, LaBelle, James L., Dickinson, Bryan C.
Publié dans J Am Chem Soc (2017)

Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies

par Bird, Greg H., Gavathiotis, Evripidis, LaBelle, James L., Katz, Samuel G., Walensky, Loren D.
Publié 2014

Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal Release

par Schnorenberg, Mathew R., Bellairs, Joseph A., Samaeekia, Ravand, Acar, Handan, Tirrell, Matthew V., LaBelle, James L.
Publié dans Materials (Basel) (2019)

Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation

par Acar, Handan, Samaeekia, Ravand, Schnorenberg, Mathew R., Sasmal, Dibyendu K, Huang, Jun, Tirrell, Matthew V., LaBelle, James L.
Publié dans Bioconjug Chem (2017)

Self-Assembling Peptide-Based Building Blocks in Medical Applications

par Acar, Handan, Srivastava, Samanvaya, Chung, Eun Ji, Schnorenberg, Mathew R., Barrett, John C., LaBelle, James L., Tirrell, Matthew
Publié dans Adv Drug Deliv Rev (2016)

Multimodal Interaction with BCL-2 Family Proteins Underlies the Pro-Apoptotic Activity of PUMA BH3

par Edwards, Amanda L., Gavathiotis, Evripidis, LaBelle, James L., Braun, Craig R., Opoku-Nsiah, Kwadwo A., Bird, Gregory H., Walensky, Loren D.
Publié 2013

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide

par Hadji, Abbas, Schmitt, Greta K., Schnorenberg, Mathew R., Roach, Lauren, Hickey, Connie M., Leak, Logan B., Tirrell, Matthew V., LaBelle, James L.
Publié dans Oncotarget (2019)

Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells

par Katz, Samuel G., LaBelle, James L., Meng, Hailong, Valeriano, Regina P., Fisher, Jill K., Sun, Heather, Rodig, Scott J., Kleinstein, Steven H., Walensky, Loren D.
Publié 2014

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

par LaBelle, James L., Katz, Samuel G., Bird, Gregory H., Gavathiotis, Evripidis, Stewart, Michelle L., Lawrence, Chelsea, Fisher, Jill K., Godes, Marina, Pitter, Kenneth, Kung, Andrew L., Walensky, Loren D.
Publié 2012

Outcomes following second allogeneic stem cell transplant for disease relapse after T cell depleted transplant correlate with remission status and remission duration after the firs...

par Fan, Yun, Artz, Andrew S., van Besien, Koen, Stock, Wendy, Larson, Richard A., Odenike, Olatoyosi, Godley, Lucy A., Kline, Justin, Cunningham, John M., LaBelle, James L., Bishop, Michael R., Liu, Hongtao
Publié dans Exp Hematol Oncol (2019)

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia

par Reynolds, Christine, Roderick, Justine E., LaBelle, James L., Bird, Gregory, Mathieu, Ronald, Bodaar, Kimberly, Colon, Diana, Pyati, Ujwal, Stevenson, Kristen E., Qi, Jun, Harris, Marian, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Neuberg, Donna S., Look, A. Thomas, Walensky, Loren D., Kelliher, Michelle A., Gutierrez, Alejandro
Publié 2014

Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity

par Volpatti, Lisa R., Wallace, Rachel P., Cao, Shijie, Raczy, Michal M., Wang, Ruyi, Gray, Laura T., Alpar, Aaron T., Briquez, Priscilla S., Mitrousis, Nikolaos, Marchell, Tiffany M., Sasso, Maria Stella, Nguyen, Mindy, Mansurov, Aslan, Budina, Erica, Solanki, Ani, Watkins, Elyse A., Schnorenberg, Mathew R., Tremain, Andrew C., Reda, Joseph W., Nicolaescu, Vlad, Furlong, Kevin, Dvorkin, Steve, Yu, Shann S., Manicassamy, Balaji, LaBelle, James L., Tirrell, Matthew V., Randall, Glenn, Kwissa, Marcin, Swartz, Melody A., Hubbell, Jeffrey A.
Publié dans bioRxiv (2021)

Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity

par Volpatti, Lisa R., Wallace, Rachel P., Cao, Shijie, Raczy, Michal M., Wang, Ruyi, Gray, Laura T., Alpar, Aaron T., Briquez, Priscilla S., Mitrousis, Nikolaos, Marchell, Tiffany M., Sasso, Maria Stella, Nguyen, Mindy, Mansurov, Aslan, Budina, Erica, Solanki, Ani, Watkins, Elyse A., Schnorenberg, Mathew R., Tremain, Andrew C., Reda, Joseph W., Nicolaescu, Vlad, Furlong, Kevin, Dvorkin, Steve, Yu, Shann S., Manicassamy, Balaji, LaBelle, James L., Tirrell, Matthew V., Randall, Glenn, Kwissa, Marcin, Swartz, Melody A., Hubbell, Jeffrey A.
Publié dans ACS Cent Sci (2021)