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Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies

Hydrocarbon stapling is a chemical approach to restoring and fortifying the natural α-helical structure of peptides that otherwise unfold when taken out of context from the host protein. By iterating the peptide sequence, staple type, and sites of insertion, discrete compositions can be generated to...

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Autores principales: Bird, Greg H., Gavathiotis, Evripidis, LaBelle, James L., Katz, Samuel G., Walensky, Loren D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131438/
https://ncbi.nlm.nih.gov/pubmed/24358963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4003305
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