Flow Cytometry-Based Detection and Analysis of BCL-2 Family Proteins and Mitochondrial Outer Membrane Permeabilization (MOMP)

Por Ludwig, Lindsey M., Maxcy, Katrina L., LaBelle, James L.
Publicado no Methods Mol Biol (2019)

Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation

Por Ludwig, Lindsey M., Nassin, Michele L., Hadji, Abbas, LaBelle, James L.
Publicado no Front Pediatr (2016)

Synthesis and Purification of Homogeneous Lipid-Based Peptide Nanocarriers by Overcoming Phospholipid Ester Hydrolysis

Por Schnorenberg, Mathew R., Yoo, Sang Pil, Tirrell, Matthew V., LaBelle, James L.
Publicado no ACS Omega (2018)

RNA Polymerase tags to monitor multidimensional protein-protein interactions reveal pharmacological engagement of Bcl-2 proteins

Por Pu, Jinyue, Dewey, Jeffrey A., Hadji, Abbas, LaBelle, James L., Dickinson, Bryan C.
Publicado no J Am Chem Soc (2017)

Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies

Por Bird, Greg H., Gavathiotis, Evripidis, LaBelle, James L., Katz, Samuel G., Walensky, Loren D.
Publicado em 2014

Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal Release

Por Schnorenberg, Mathew R., Bellairs, Joseph A., Samaeekia, Ravand, Acar, Handan, Tirrell, Matthew V., LaBelle, James L.
Publicado no Materials (Basel) (2019)

Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation

Por Acar, Handan, Samaeekia, Ravand, Schnorenberg, Mathew R., Sasmal, Dibyendu K, Huang, Jun, Tirrell, Matthew V., LaBelle, James L.
Publicado no Bioconjug Chem (2017)

Self-Assembling Peptide-Based Building Blocks in Medical Applications

Por Acar, Handan, Srivastava, Samanvaya, Chung, Eun Ji, Schnorenberg, Mathew R., Barrett, John C., LaBelle, James L., Tirrell, Matthew
Publicado no Adv Drug Deliv Rev (2016)

Multimodal Interaction with BCL-2 Family Proteins Underlies the Pro-Apoptotic Activity of PUMA BH3

Por Edwards, Amanda L., Gavathiotis, Evripidis, LaBelle, James L., Braun, Craig R., Opoku-Nsiah, Kwadwo A., Bird, Gregory H., Walensky, Loren D.
Publicado em 2013

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide

Por Hadji, Abbas, Schmitt, Greta K., Schnorenberg, Mathew R., Roach, Lauren, Hickey, Connie M., Leak, Logan B., Tirrell, Matthew V., LaBelle, James L.
Publicado no Oncotarget (2019)

Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells

Por Katz, Samuel G., LaBelle, James L., Meng, Hailong, Valeriano, Regina P., Fisher, Jill K., Sun, Heather, Rodig, Scott J., Kleinstein, Steven H., Walensky, Loren D.
Publicado em 2014

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

Por LaBelle, James L., Katz, Samuel G., Bird, Gregory H., Gavathiotis, Evripidis, Stewart, Michelle L., Lawrence, Chelsea, Fisher, Jill K., Godes, Marina, Pitter, Kenneth, Kung, Andrew L., Walensky, Loren D.
Publicado em 2012

Outcomes following second allogeneic stem cell transplant for disease relapse after T cell depleted transplant correlate with remission status and remission duration after the firs...

Por Fan, Yun, Artz, Andrew S., van Besien, Koen, Stock, Wendy, Larson, Richard A., Odenike, Olatoyosi, Godley, Lucy A., Kline, Justin, Cunningham, John M., LaBelle, James L., Bishop, Michael R., Liu, Hongtao
Publicado no Exp Hematol Oncol (2019)

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia

Por Reynolds, Christine, Roderick, Justine E., LaBelle, James L., Bird, Gregory, Mathieu, Ronald, Bodaar, Kimberly, Colon, Diana, Pyati, Ujwal, Stevenson, Kristen E., Qi, Jun, Harris, Marian, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Neuberg, Donna S., Look, A. Thomas, Walensky, Loren D., Kelliher, Michelle A., Gutierrez, Alejandro
Publicado em 2014