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Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation

A crucial component of regulating organismal homeostasis is maintaining proper cell number and eliminating damaged or potentially malignant cells. Apoptosis, or programed cell death, is the mechanism responsible for this equilibrium. The intrinsic apoptotic pathway is also especially important in th...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Ludwig, Lindsey M., Nassin, Michele L., Hadji, Abbas, LaBelle, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5174130/
https://ncbi.nlm.nih.gov/pubmed/28066751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2016.00135
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