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Synthesis and Purification of Homogeneous Lipid-Based Peptide Nanocarriers by Overcoming Phospholipid Ester Hydrolysis

[Image: see text] Despite the therapeutic promise of phospholipid-based nanocarriers, a major obstacle to their widespread clinical translation is a susceptibility to fatty acid ester hydrolysis, leading to lack of quality control and inconsistencies in self-assembly formulations. Using electrospray...

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Publicado en:ACS Omega
Main Authors: Schnorenberg, Mathew R., Yoo, Sang Pil, Tirrell, Matthew V., LaBelle, James L.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2018
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210079/
https://ncbi.nlm.nih.gov/pubmed/30411059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01772
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